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Slide#1
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Slide#2
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We introduced new laboratory automation systems from the following concepts,
first is the ultra-multi-analyzer consisting of many analyzers of different
analytical fields.
Second is transportation system using a single line/belt without reduction
of analytical speed. Third is automated re-testing system for reducing
labor of technicians and improving test efficiency. Forth is twenty-four
hour testing system including STAT tests. The last is Back-up system using
different type of analyzer, but same reagents |
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Slide#3
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We had a old conventional system for laboratory automation system as shown
in this slide, this kind of system may decided by cost or technical reason
or sectionalism of old style laboratory. We discussed the other laboratory
automation system, tree structure system. One intensive starting unit,
but aliquot the specimen for several lines. These two systems have following
disadvantages, problems. The first is low efficiency. On considering a
cost for system, it is too low efficiency. Second s increase of required
sample volume. It needs a aliquot for each lines, and this means an increase
of dead volume. In some of the existing hospital, sample volume become
double when they start to use these systems.
Third is too large space is required. Many of existing laboratory does
not have enough space to have such systems. In Tokyo, especially surrounding
our hospital, land cost is very expensive, and we have small space for
laboratory. Fourth, system itself is so large, the cost for transportation,
belt line, may be large. We discussed many times and reached to accept
the single line system for laboratory automation system, CLINILOG. |
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Slide#4
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Slide#5
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This is the overview of our laboratory system. Our system misses some of
important components, such as centrifuge unit, EIA analyzer and electrophoresis.
These units can be connect to this system, but some reasons stopped us
to connect these units.
Our room for laboratory automation system is very small as mentioned earlier,
we have no space to connect EIA analyzers and electrophoresis system. Automated
centrifuge system is not suitable to random processing. Almost of existing
centrifuge units are just accord with batch processing. Therefore, if we
require both the automated centrifugation and random processing, we must
have 2 or more automated centrifuge units. Then, the system cost is getting
large. We have all laboratory sections, such as chemistry, hematology,
serology/immunology, and so on. Today, I would like to focus my talking
in the chemistry, serology/immunology, and coagulation units, we constructed
a so called ultra-multi-analyzer for these units. |
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Slide#6
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You can see a large number of analyzers and a few technician. |
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Slide#7
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From ward of the hospital or the central blood collecting room, blood or
urine come to the laboratory. |
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Slide#8
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Technicians check a sample if they have micro-coagulation in hematology,
or fibrin clot after centrifugation. |
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Slide#9
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This is the start stocker. The sample is set here and bar-code of each
sample is read. In the transportation line, the sample is recongnized and
controlled only by rack ID. We don't need to read sample ID at each analyzer
and can save time and reduce reading error. If the bar-code reading error
is occurred, the rack will be ejected. So, unknown rack will never be exist
in the transportation line. |
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Slide#10
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Slide#11
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This is the special starting line for STAT test. STAT sample has a priority
to routine sample to get a line for analysis. |
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Slide#12
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This is the de-cap unit. We use film type de-cap unit. |
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Slide#13
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Slide#14
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unit. Pipette a sample to ON-line and OFF-line sample cups. |
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Slide#15
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Slide#16
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Slide#17
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This is the coagulation analyzer, Coagrex 700 from |
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Slide#18
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Slide#19
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These are glucose analyzer and electrolyte analyzer from A&T corporation.
We can measure glucose of OGTT by this glucose analyzer. |
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Slide#20
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Slide#21
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will cover special chemistries, urine chemistry, special protein analysis,
and some coagulation testing. |
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Slide#22
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Slide#23
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Slide#24
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One is the Toshiba 80FR. We use this analyzer in routine chemistry and
STAT in the mid-night as talking later. |
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Slide#25
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Slide#26
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This is the structure of real-time re-run for Toshiba 80 FR. After sampling,
the sample is waiting at the rack buffer unit. When the result is obtained
and if re-run is necessary, the sample will return to sampling position
by reverse transportation. |
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Slide#27
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Another is the Hitachi 7350, as the same analyzer as Hitachi 747-300 in
USA. This can measure 360 test per hour, so we use as routine chemical
testing |
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Slide#28
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This is the Coulter counter Gen-S, we have 4 Gen-S. |
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Slide#29
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Slide#30
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This is the terminal stoker, which stock the sample, mother sample.
Technician can easy storage sample from the terminal stocker. The samples
will be storage at refrigerator for 7 days. |
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Slide#31
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Slide#32
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This is the list of test items. Hitachi will cover the routine chemistry,
and the 502X will special chemistry, such as myoglobin, immunglobulines,
complement, and so on. TBA cover mainly the components in urine, such as
creatinine, urea |
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Slide#33
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For the 24 hour service, technician stay at the laboratory in the mid-night.
We have 75 technicians in our laboratory. They are working at the different
fields of laboratory, such as surgical pathology, microbiology, ECG, and
so on. They are not familiar with the operating analyzers. They can easy
run the testing by just setting the sample in the rack. Before developing
this system, test items were very limited, but now we can measure almost
same items if we want. |
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Slide#34
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The size of our system is about 63 feet by 22 feet. We are sure this system
is very compact and have a big enough power for laboratory test |
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Slide#35
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Our transportation system has unique unit for connecting aliquot unit and
analyzers. This is a so called elevator unit, aliquot or STAT sample go
up and down by elevator from aliquot unit to analyzer. By this unit, technician
can easily enter the ultramulti-analyzer unit and inspect the analyzers. |
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Slide#36
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As shown in this picture, all analyzers are connecting by Local Area Network
(LAN), and personnel computer will communicate with Laboratory Information
System through one port. Therefore, from the view point of Laboratory information
System, our system seems just a ultramulti-analyzer. And as you can see,
we could minimize the Laboratory information system also.
In our system, information and sample flow are comprehensively controlled.
If one result must reflects to another testing, we can treat those irregular
transportation of sample. |
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Slide#37
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In our old system, we needed 14 medical technicians for sample reception,
chemistry, serology/immunology, coagulation, and STAT testing. By using
our integrated ultramulti-analyzer, the same job may be covered by 8 technicians.
They are working at the central blood collecting room, now. |
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Slide#38
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This is the specimen flow in case if the same sample material is set to
the rack. Serum, plasma or urine sample will go to de-cap unit, if necessary,
and go to aliquot unit. In the aliquot unit, necessary volume of sample
is calculated by testing order, and pipette to each sample cups. Off-line
sample will be taken manually to each analyzer, such as EIA for hormones
and electrophoresis. On-line sample will go to necessary analyzer, and
original, mother sample will directly go to terminal stocker. On-line and
off-line aliquot is made simultaneously. The 502X and glucose analyzer
have re-run function. Although TBA and Hitachi don't have re-run function.
By an intelligent function of transport unit, we realize a real-time re-run.
STAT samples take a another line, they go to the de-cap unit then go through
aliquot unit and reach the analytical unit. |
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Slide#39
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This is the conclusion of introduction so called ultramulti-analyzer using
single line.
First is reducing the labor. The number of technician is reduced 13 to
8.Second, turnaround time of analysis is reduced 40 to 30 minutes, and
we can measure the essential test for consultation, such as glucose, before
medical consultation. The patients come to the central blood collecting
room, drawing blood. The test result will be returned to the CRT in the
physician's personnel computer during their waiting. Physicians are very
happy to get the laboratory data reflected the present status. They can
easy make accurate consultation.
Third is the mid-night testing. Before introduction of this system, we
could just 10 items, but we can 18 items including FDP. And we can use
the same reagent as routine testing, that lead us cost saving. |
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